The Claude API. Best-in-class long context, prompt caching, and the only major vendor shipping a working "computer use" agent.
The Anthropic API exposes the Claude model family — Opus 4.5 (flagship reasoning), Sonnet 4.5 (balanced), and Haiku 4.5 (fast/cheap). It's the second-most-used LLM API in 2026, and in several niches (long-context analysis, agentic tool use, "computer use" agents, and writing that has to sound human) it's the first choice. Claude's defining trait is that it follows long, complex instructions precisely — 200K-token context windows that actually work, not just on the spec sheet.
Who it's for: Teams building agents, RAG over long documents, code review bots, and any workflow where instruction-following matters more than raw throughput. Also the only major API offering a sandboxed "computer use" mode where the model can click, type, and browse on your behalf.
The core endpoint. Send messages, get a response. Supports system prompts, multi-turn, vision (images and PDFs), and native tool use (function calling). Streaming via SSE. Output up to 64K tokens in a single response — the longest of any major model.
Cache any prefix — system prompt, knowledge base, few-shot examples — and pay ~10% of normal input cost on cache hits. For RAG-heavy apps with a fixed knowledge base, this cuts the bill 80-90%. Cache TTLs of 5 minutes or 1 hour.
Native function calling with parallel tool calls. The unique feature is "computer use" beta — Claude can move a mouse, click, type, and navigate a virtual desktop. Powers most of the autonomous-agent demos you've seen in 2026.
Upload large documents (up to 500MB) for analysis, and run Batch API jobs at 50% off list price with 24-hour turnaround. Useful for nightly document processing, bulk classification, and large-corpus analysis.
| Model | Input / 1M tok | Output / 1M tok | Cache write | Cache read |
|---|---|---|---|---|
| Claude Opus 4.5 | $15.00 | $75.00 | $18.75 | $1.50 |
| Claude Sonnet 4.5 | $3.00 | $15.00 | $3.75 | $0.30 |
| Claude Haiku 4.5 | $0.80 | $4.00 | $1.00 | $0.08 |
| Batch API (all models) | 50% off | 50% off | — | — |
All Claude models ship a 200K-token context window. Opus 4.5 supports 1M-token context in beta for enterprise customers. Cache reads are the secret weapon — at $0.08/1M tokens on Haiku, RAG over a cached knowledge base is effectively free.
If your app needs an agent that follows complex instructions, reasons over long documents, or drives a browser, the Anthropic API is the best choice in 2026. Pair it with the OpenAI API for the things Anthropic doesn't do (image generation, embeddings, Whisper) and you have the strongest two-provider stack available. Prompt caching alone justifies the switch for any RAG-heavy workload.
GPT-5, Whisper, embeddings — the most-used LLM API. The natural pair to Claude.
Anthropic's flagship reasoning model. The single model you'd call via this API for hard tasks.
Balanced Claude model — the default for most production traffic.
Prompt management and evals layer that sits on top of the Anthropic + OpenAI APIs.